Combined Protocol

RegenXellence

Excellence In Natural Healing

A science-backed protocol combining multiple autologous treatments for synergistic regenerative results. Developed to help doctors treat chronic pain patients more effectively without the side effects of conventional solutions.

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Mechanism

How The Protocol Works

Three complementary autologous therapies combine for comprehensive regenerative healing.

ACS (RegenX)

Pain Control

Reduces pain through anti-inflammatory cytokines
IL-1Ra neutralizes cartilage-destroying IL-1
Decreases prostaglandin production via COX-2 inhibition
Upregulates TGF-β to resolve inflammation

Liquid PRF

Growth Factors

Concentrated PDGF, EGF, VEGF growth factors
Induces stem cell recruitment and proliferation
Activates resident cell matrix synthesis
Enhances the healing microenvironment

Stem Cells

Tissue Repair

Paracrine actions reduce inflammation
Stimulates angiogenesis through cytokines
Differentiates into replacement cell types
Facilitates comprehensive tissue healing

Protocols

Treatment Levels

Two protocol levels based on disease severity, combining multiple autologous therapies for optimal results.

Level 1

Without Stem Cells

Day 0

RegenX Serum

Remove/decrease pain

Day 30

Liquid PRF Shot #1

Support regenerative activity

Day 60

Liquid PRF Shot #2

Continue regeneration

Day 90

Liquid PRF Shot #3

Complete regenerative cycle

Level 2

With Stem Cells

Day 0

RegenX Serum

Remove/decrease pain

Day 30

Stem Cell Injection

Regenerative cell delivery

Day 60

Liquid PRF Shot #1

Support stem cell activity

Day 90

Liquid PRF Shot #2

Enhance regeneration

Day 120

Liquid PRF Shot #3

Complete healing cycle

Indications

Treatable Conditions

Science-backed indications for the RegenXellence combined protocol.

Osteoarthritis (knee, hip, shoulder, ankle)

Tendinopathy (rotator cuff, patellar, Achilles)

Cartilage injuries and defects

Ligament injuries (ACL, MCL sprains)

Degenerative spine changes

Intervertebral disc damage

Muscle tears and strains

Nerve compression injuries

Evidence

Supporting Clinical Studies

Jansen et al.(2018)

Significant reductions in pain and improvements in function up to 6 months post-injection with ACS, BM-MSCs, and liquid PRF for knee osteoarthritis.

Halpern et al.(2017)

Significant improvements in pain/function at 3 and 6 months with intra-articular ACS, adipose-derived stem cells, and liquid PRF.

de Campos et al.(2018)

Complete resolution of Achilles tendinopathy symptoms and return to full activities at 6 months using combined ACS, BM-MSCs, and liquid PRF.

Peerbooms et al.(2020)

Review demonstrating synergy between ACS, PRP/PRF, and stem cells for regenerative orthopedic applications due to complementary mechanisms.

Implement RegenXellence in Your Practice

Get trained on the complete protocol with hands-on guidance and clinical support.

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